Assessing cell-material interactions on a novel biodegradable elastomer

Introduction The characterization of cellular interactions with a biomaterial surface is important to the development of novel biomaterials. Traditional methods used to characterize processes such as cell adhesion, retention, growth, and phenotypic differentiation on biomaterials are time consuming, destructive, and do not allow for in situ quantitative assessment. The overall goal of this research is to describe the interactions between cells and a newly developed biodegradable elastomeric biomaterial using a technique referred to as 4-D elastic lightscattering fingerprinting (4D-ELF).